Cipher: 2404
Nomenclature: Genomic manipulation in aquaculture
Study programme: Molecular biosciences
Module: Marine Biology
Case holder:

Prof.dr.sc. Branko Glamuzina
Institution of the case holder:

University of Dubrovnik
Contributors - Contractors:
Subject status: Electoral College
The year in which the case is submitted: Year I
The semester in which the case is submitted: Semester II
Subject objective:

To understand the application of genomic manipulation in aquaculture for the purpose of obtaining organisms with better features than parents, and to understand the use of these organisms in breeding practice.
Case contents:

Introduction to genetic methods used in modern aquaculture production. Advantages and disadvantages of traditional and modern methods of genomic and gene manipulation. Hybridization and polyploidium in aquaculture. Ways to get triploid and tetraploid fish and bivalves. Overview of successful hybrid combinations in breeding practice. Technological and economic features of genomic manipulation.
Genetically modified organisms in aquaculture, status and perspectives. Methods of production of GMOs in aquaculture. The dangers and benefits of introducing GMO fish into breeding practice.
Learning outcomes: competences, knowledge, skills that the subject develops:

1. To establish the scientific and methodological basis for the work on genomic and gene manipulation of aquatic organisms.
2. Examine the technological and economic reasons for the application of genomic and gene manipulation of aquatic organisms.
3. Choose the best examples of successful hybrids, triploids and tetraploids for their application in breeding practice.
4. Critically judge the current status of GMO technology in aquaculture as well as the pros and cons of its application.
ECTS Credits 6
Lectures 5
Seminars (IS) 5
Exercises (E) 20
Altogether 30
The way of teaching and acquiring knowledge:

Regular attendance, preparation and presentation of seminar work, attendance of oral and/or written exams
Ways of teaching and acquiring knowledge: (notes)
Monitoring and evaluating students (mark in fat printing only relevant categories) Attendance, Mandatory seminar work
Rating method: Written exam, Oral exam, Essay/Seminar, Analysis of published publication, 9
Mandatory literature:

1. Zanuy, S., Carrillo, M., Bla ́zquez, M., Ramos, J., Piferrer, F., Donaldson, E.M. Production of monosex and sterile sea bass by hormonal and genetic approaches. Publ. Assoc. Dev. Aquacult. 119, 409–423.
2. Lee, C.-S., O'Bryen, P. (Eds.), 2001. Advanced Biotechnology in Hatchery Production. Aquaculture, ox. 200, pp. 1 –250.
3. Felip, A., Zanuy, S., Carrillo, M., Piferrer, F., 2001. Induction of triploidy and gynogenesis in teleost fish with emphasis on marine species. Genetics 111, 175–195.
4. Gendreau, S., Grizel, H., 1990. Induced triploidy and tetraploidy in the European flat oyster, Ostrea edulis L. Aquaculture, 90: 229-238.
5. Beardmore, J.A.; Porter, J.S., 2003. Genetically modified organisms and aquaculture. FAO Fisheries Circular. No. 989. Roma, FAO. 2003. 38p.
Supplementary (recommended) literature:

In view of the expressed interests of students in individual groups of organisms, supplementary literature will be selected from primary scientific aquaculture journals ("Aquaculture", "Aquaculture Research" and the like)
How to monitor the quality and performance performance (evaluation):

Discussion with students and colleagues, evaluation of performance by the joint expert committee of the Institute "Ruđer Bošković", the University of Dubrovnik and the University of Osijek.
Surveys of students after teaching.