Cipher: 1005
Nomenclature: Molecular biology of the cell
Study programme: Molecular biosciences
Module: Compulsory course
Case holder:

Prof.dr.sc. Hrvoje Lepeduš
the prof.dr.sc. Coral Gall Trošelj, ren.advisor
Institution of the case holder:

(HL) Faculty of Humanities and Social Sciences, Josip Juraj Strossmayer University of Osijek; Faculty of Dental Medicine and Health, J.J. Strossmayer University of Osijek
(KGT) Ruđer Bošković Institute
Contributors - Contractors:

the doc.dr.sc. Lidija Milković, associate
Subject status: Compulsory course
The year in which the case is submitted: Year I
The semester in which the case is submitted: Semester I
Subject objective:

To understand the dynamic connection between cell structures and their functioning as well as the continuity of cellular processes and to support the conceptual understanding of the functioning of the cell at the molecular level using modern scientific knowledge.
Case contents:

Chemical composition of the cell. Overview plan of the cellular organization: protocites, eucytes. Organization and chemism of the biomembrane. Forms of transport through the biomembrane. A cytoskeleton. Structure and function of the interphase nucleus: chromosomes, DNA and genes. Control of gene expression. The cell cycle. Replication. Transcription. Mitosis and endomitosis. Mejoza and crossing-over. Endoplasmic reticulum, ribosomes and protein biosynthesis. Golgi system, lysosomes, peroxisomes, glioxsisomes, vacuoles. Mitochondria: ultrastructure and function. Cellular energy. Plasticides and plastic pigments. Ultrastructure of chloroplasts and photosynthesis. Cell differentiation and growth control. Molecular mechanisms that lead to the development of cancer. The peculiarities of cancer cell metabolism.
Learning outcomes: competences, knowledge, skills that the subject develops:

1. Apply basic knowledge about the structure, structure and function of the cell in explaining the molecular basis of the living world.
2. Predict the connection between the structure, structure and function of the cell as well as the continuity of cellular processes.
3. Consult the scientific literature and critically judge the methodology of modern scientific research and results that lead to new scientific knowledge about the structure and function of cells and about life processes at the molecular level.
ECTS Credits 4
Lectures 15
Seminars (IS) 5
Exercises (E) 5
Altogether 25
The way of teaching and acquiring knowledge:

Students are obliged to attend lectures and exercises or consultations, and to prepare seminars on selected topics.
Ways of teaching and acquiring knowledge: (notes)
Monitoring and evaluating students (mark in fat printing only relevant categories) Attendance, Teaching activities, Mandatory seminar work
Rating method: Oral exam, Essay/Seminar, 9
Mandatory literature:

ALBERTS, A., JOHNSON, A., LEWIS, J., RAFF, M., ROBERTS, K., WALTER, P., 2007: Molecular biology of the cell. 5th ed. Garland Science, New York - Abingdon.
COOPER, G.M., HAUSMAN, R.E., 2010: Cell – molecular approach. Fifth edition. (Croatian editor: Lauc, G.) Medical publishing Zagreb.
MURRAY, R.K., BENDER, D.A., BOTHAM, K.M., KENNELLY, P.J., RODWELL, V.W., WEIL, P.A., 2011: Harper's Illustrated Biochemistry. 28th edition. (Editors of the Croatian edition: Lovrić, J., Sertić, J.) Medical publishing Zagreb.
LEPEDUŠ, H., CESAR, V., 2010: Basics of plant histology and anatomy of vegetative organs. University of J. J. Strossmayer in Osijek, Department of Biology, Osijek.
Supplementary (recommended) literature:

REECE, J.B., URRY, L.A., CAIN, M.L., WASSERMAN, S.A., MINORSKY, P.V., JACKSON, R.B., 2013: Campbell biology. 10th ed. Pearson - Benjamin Cummings, San Francisco.
VOET, D., VOET J.G., 2010: Biochemistry, 4th ed. John Wiley & Sons, Inc. York.
AMBRIOVIĆ RISTOV, A., 2007: Methods in molecular biology. Ruđer Boskovic Institute, Zagreb.
How to monitor the quality and performance performance (evaluation):

The success of the course will be evaluated annually by the joint expert committee of the Ruđer Boskovic Institute, the University of Dubrovnik and the University of Josip Juraj Strossmayer in Osijek based on exam success and surveys.